קרן הורמן

תלמידת המחלקה לתואר שני תרצה בנושא:

Parametric Electrical Impedance Tomography for Monitoring Pulmonary Edema in CHF Patients with an Implantable Device– A Theoretical Study

Congestive Heart Failure (CHF) is a complex clinical condition in which the heart fails to produce enough cardiac output, which often results in pulmonary congestion. Cardiac Resynchronization Therapy (CRT), also known as biventricular-pacemaker, is nowadays a highly recommended therapy for heart failure patients. Since the CRT can monitor parameters such as impedance, detection of pulmonary edema using this device is possible with the bio-impedance technique. In this study, the ability of the parametric Electrical Impedance Tomography (pEIT) scheme and the intra-thoracic impedance technique to monitor lung fluid status in patients with implantable pacemaker was compared using simulation in a theoretical model of the thorax. Applying the pEIT scheme and the intra-thoracic impedance technique in a computerized three-dimensional model of the thorax demonstrates that the pEIT converges to the exact values of lung conductivity with a sensitivity of 1400 % change/S/m. The intra-thoracic impedance has a lower sensitivity of 190 % change/S/m for edema in both lungs and in case of unilateral left lung edema and a very low sensitivity of 5 % change/S/m when unilateral right lung edema is present. The double-frequency intra-thoracic impedance has a sensitivity of 420 % change/S/m for edema in both lungs and in case of unilateral left lung edema and a very low sensitivity of 8 % change/S/m when unilateral right lung edema is present. The pEIT method requires a SNR greater than 70dB and can bear up to ±2mm change in electrode location. In conclusion, the simulation results suggest that the pEIT may be applicable for monitoring lung fluid status in patients with implantable pacemaker with greater sensitivity than the intra-thoracic technique.

העבודה נעשתה בהנחייתו של פרופ' שמעון עבוד, המחלקה להנדסה ביו-רפואית,

אוניברסיטת תל-אביב

ההרצאה תתקיים ביום ראשון 20.5.2012, בשעה 14:45,

בחדר 315, הבניין הרב תחומי, אוניברסיטת תל אביב