Dr. Ronny Bartsch

Division of Sleep Medicine, Harvard Medical School

Network Physiology:

Mapping interactions between complex physiological systems

The human organism is an integrated network where complex physiological systems, each with its own regulatory mechanisms, continuously interact, and where failure of one system can trigger a breakdown of the entire network. 
Identifying and quantifying dynamical networks of diverse systems with different types of interactions is a challenge. We propose a framework to probe interactions among diverse systems, and we identify a physiological network. 
We find that each physiological state is characterized by a specific
network structure, demonstrating a robust interplay between network topology and function. Across physiological states, the network undergoes topological transitions associated with fast reorganization of physiological interactions on time scales of a few minutes, indicating high network flexibility in response to perturbations. The proposed system-wide integrative approach may facilitate the development of a new field, Network Physiology.

ההרצאה תתקיים ביום ראשון, 7.4.2013, בשעה 14:45,

חדר 315, הבניין הרב-תחומי, אוניברסיטת תל-אביב