Journal of Microwave Power and Electromagnetic Energy (JMPEE)
TITLE	Increasing Antigenecity of B16 Melanoma Cell Fraction with Microwave Hyperthermia [PDF]
AUTHORS	R. Santini, M. Hosni, T. Douss, P. Deshaux and H. Pacheco 1986 21 1 41-44
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Abstract An injection of a fraction of a fraction (mw) obtained by centrifugation at 30 kg of homogenate of B16 melanoma cells, treated with microwave hyperthermia (2450 MHz, CW, 44°C, for 20 minutes), increases the survival time (p < 0.01) of C57-BL/6J male mice inoculated 26 days later with cells (viability > 95%) :of B16 melanoma. The delay of 26 days between these two injections corresponds to the moment where the synthesis of immunoglobulins is increased in protected mice. The earliest death (p < 0.001) of animals injected with untreated tumoral cell fraction (), and that received a suspension of viable B16 melanoma cells () can be explained by an inhibition of humoral immunity system.