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  Implantable medical devices can provide life-giving help to many systems in the body. When made of a biodegradable polymer, such devices degrade with time and the end products are nontoxic. These devices can remain intact in the body for a predicted period of time - from weeks to years - and then degrade without the need for surgical removal. We have been developing multifunctional biodegradable implants (active implants) that combine tissue regeneration (or support) with local controlled drug release. The basic elements of our active implants are drug-eluting fibers and drug-eluting films. We investigate the effects of the kinetic and thermodynamic parameters in the preparation process on the microstructure and on the resulting properties (drug release profile, mechanical properties, biocompatibility etc.). The results of our studies thus have great medical relevance and are aimed to provide solutions to basic needs in the fields of medical implants and tissue regeneration.



Biomaterials Laboratory
Multi-disciplinary Building
Room 416
Tel: +(972)-3-6405841
 
  Prof. Meital Zilberman's
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Department of
Biomedical Engineering

 

 












 
Last Updated May 10, 2007